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タイトル 自然免疫の異物識別機構への理解を促すTLRカードゲームの開発<数学・自然科学>
別タイトル
TLR Card Game : Developed for Understanding Pathogen Recognition by the Innate Immune System
著者
日比野, 拓 (HIBINO, Taku)
埼玉大学教育学部自然科学講座 (Faculty of Education, Saitama University)
[出版社版]
出版者 埼玉大学教育学部
日付
出版年: 2016 - 2016
作成日: 2016-10-10
更新日
上位タイトル
埼玉大学紀要. 教育学部 (Journal of Saitama University. Faculty of Education). Vol.65, No.2  (2016. ) ,p.261- 270
識別番号
ISSN
18815146
抄録 Toll-like receptors (TLRs) are protein sensors located on immune cells, which function as pathogen recognition by the innate immune system. These TLRs form a homodimer or a heterodimer, which recognizes distinct pathogen-associated molecular patterns. The explanation of the TLRs and their function have been introduced on Japanese biological textbooks for high school students since 2012. Here, I developed a card game, TLR Card Game, as an educational material for understanding the mechanism of the innate pathogen recognition. The TLR Card Game is for multiplayers who are surrounding a table where several pairs of a phagocytic cell board and a pathogen card are set. Each player has to present two TLR cards from his own hand in his turn, making a TLR dimer corresponding to a pathogen card presenting on the table. When a TLR card-pair is presented correctly, a player can get several points, and the player with highest points finally gets win. The TLR Card Game was carried out in an extracurricular class of a high school in Saitama City. The effectiveness of the game was assessed by open- and close-ended questionnaires for 30 students. All the students got interested in the TLR Card Game and its immunology. Some students, however, answered that the game and the immune mechanism were not much linked in their thought. The TLR Card Game is considered useful for students attracted towards immunology, but the instructions before use needed to be improved.
キーワード
自然免疫
トル様受容体
TLR
高校生物
教材開発
Toll-like receptors
TLR
innate immunity
biological education
言語
jpn
資源タイプ text
ジャンル Departmental Bulletin Paper
著者版フラグ publisher
Index
/ Public / 埼玉大学 / 教育学部
/ Public / 主題別 / 社会科学 / 教育学 / 教科教育学
/ Public / ジャンル別 / 研究紀要 / 埼玉大学 / 教育学部紀要
/ Public / 主題別 / 生物学 / 生物科学 / 構造生物化学
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